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  • A new drug approved for weight-loss by the U.S. Food and Drug Administration had achievement in many studies, nonetheless it isn't a panacea to lose weight. It must be found in combination with a low-calorie diet and frequent exercise in order to be effective. Using two separate drugs to shed weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you ought to err assisting caution and permit the FDA do its job and demand some research be done so the public knows the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on his or her medications. Researchers discovered that participants taking this drug for the year, lost weight within four weeks and have kept the weight off throughout the 56 weeks from the study. Contrave is really a combination from the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of many active ingredient, which can make them far better and safer. Combo-pilling will be the newest fad or in addition to this the newest ahead under scrutiny and for that reason it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills has become popular will be the fact that since right now there are no long term prescription diet pills that have been authorized by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug can also raise blood pressure levels and pulse rate, and must not be used in people who have a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure and heartbeat and must not be used in patients with uncontrolled high hypertension, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients on the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. Other people who must avoid using Contrave are patients suffering from bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave shouldn't be prescribed for girls who are pregnant or wanting to become pregnant.